NITROGEN OXIDE RELEASING PRODRUGS AS ANTIINFLAMMATORY, ANTICANCER AND CARDIOPROTECTIVE AGENTS

NITROGEN OXIDE RELEASING PRODRUGS AS ANTIINFLAMMATORY, ANTICANCER AND CARDIOPROTECTIVE AGENTS

This dissertation focuses on chemical and biological evaluation of diazeniumdiolate based nitrogen oxide releasing prodrugs. Three projects are described. i. Synthesis and biological evaluation of a series of new nitroxyl (HNO) releasing non-steroidal antiinflammatory drugs (NSAIDs) and comparison t...

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Bibliographic Details
Main Author: Basudhar, Debashree
Other Authors: Miranda, Katrina M.
Language:en
Published: The University of Arizona. 2011
Subjects:
aspirin
cancer
Cyclooxygenase
Nitric oxide
Nitroxyl
NSAID
Online Access:http://hdl.handle.net/10150/145745

Internet

http://hdl.handle.net/10150/145745

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