ATM Kinase and BLM Helicase: A Regulator and Key Player in Microhomology-Mediated End Joining
Microhomology-mediated end joining (MMEJ) is a class of DNA repair used to join DNA ends following a double-strand break (DSB). It represents an unfavorable and error-prone pathway because it results in deletion of nucleotides between microhomologies, as well as the deletion of one microhomology. Th...
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| Language: | en |
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The University of Arizona.
2010
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| Online Access: | http://hdl.handle.net/10150/146020 |