MECHANISMS OF THE AGE-RELATED DIFFERENCES IN MORPHINE'S EFFECTS ON THERMOREGULATION, ANALGESIA, RESPIRATORY DEPRESSION AND THERMIC TOLERANCE IN RATS.

Thermoregulatory, analgesic and respiratory depressive responses as well as tolerance to morphine were investigated in young (3 to 5 months), mature (10 to 12 month) and senescent (26 to 28 month) male Fischer 344 rats. The thermoregulatory system of senescent rats was not able to maintain body temp...

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Bibliographic Details
Main Author: MCDOUGAL, JAMES NELSON, III.
Language:en
Published: The University of Arizona. 1982
Subjects:
Online Access:http://hdl.handle.net/10150/184181