Structural and functional characterization of dog liver cytochromes P-450
I. Chloramphenicol (CAP) is a potent and selective mechanism-based inactivator of the major phenobarbital (PB)-inducible form of dog liver cytochrome P-450 (PBD-2) in vitro. In a reconstituted system, CAP inactivates PBD-2 in a time- and NADPH-dependent manner and binds covalently to the protein moi...
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| Language: | en |
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The University of Arizona.
1989
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| Online Access: | http://hdl.handle.net/10150/184775 http://arizona.openrepository.com/arizona/handle/10150/184775 |