Design and synthesis of oxytocin agonists based on molecular mechanics and computer modeling.
Some space-constraining amino acid-containing oxytocin analogues were synthesized, of which the biological activities were found to be remarkably consistent with the predictions based on molecular mechanics calculations using the CHARMM program. Correlations of the biological activities and computer...
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| Language: | en |
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The University of Arizona.
1990
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| Online Access: | http://hdl.handle.net/10150/185240 |