Immunochemical studies of malondialdehyde-altered macromolecules in cholesterol-fed New Zealand white rabbits.
Malondialdehyde (MDA), a product of lipid peroxidation and arachidonic acid metabolism, can react with free amino groups to form crosslinks which may form neoantigens and result in autoantibody production. Under hyperlipidemic conditions, excess MDA produced endogenously could conjugate with protein...
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| Language: | en |
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The University of Arizona.
1992
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| Online Access: | http://hdl.handle.net/10150/185856 |