Ethonafide-Induced Cytotoxicity is Mediated by Topoisomerase II Inhibition in Human Prostate Cancer Cells
Ethonafide is an anthracene-containing derivative of amonafide that belongs to the azonafide series of anticancer agents. The lack of cross-resistance in MDR-expressing cancer cell lines and the absence of a quinone and hydroquinone moiety make ethonafide a possible less-cardiotoxic replacement for...
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| Language: | EN |
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The University of Arizona.
2006
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| Online Access: | http://hdl.handle.net/10150/194367 |