Imexon and Gemcitabine: Mechanisms of Synergy against Human Pancreatic Cancer

Imexon is an iminopyrrolidone aziridine which previously has shown activity against a variety of human cancer types, including multiple myeloma and pancreatic adenocarcinoma. Recently, mechanistic studies in the MIA PaCa-2 human pancreatic cancer cell line have demonstrated binding to sulfhydryls, b...

Full description

Bibliographic Details
Main Author: Roman, Nicholas
Other Authors: Dorr, Robert T.
Language:EN
Published: The University of Arizona. 2005
Subjects:
Online Access:http://hdl.handle.net/10150/194494