Distinct Functions of MEKK3 and MEKK4 in Heart Valve Morphogenesis

Congenital heart defects (CHDs) occur in 5% of births. While gene mutations have been identified in CHD patients, not much is known about coordinated signaling mechanisms during heart morphogenesis. Endocardial cushions of the atrioventricular canal and outflow tract contribute to the formation of...

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Bibliographic Details
Main Author: Stevens, Mark V.
Other Authors: Camenisch, Todd D.
Language:EN
Published: The University of Arizona. 2008
Subjects:
Online Access:http://hdl.handle.net/10150/194848