The Regulation of Th2 Cytokine Genes: Functional and Comparative Genomic Analysis

Immune responses to extracellular pathogens are mediated by the Th2 cytokines Interleukin (IL)-4, IL-5 and IL-13, which are typically expressed by T helper type-2 (Th2) cells. The genes for IL4, IL5 and IL13 are grouped together within 150 kb of human chromosome 5q31, and their expression is regulat...

Full description

Bibliographic Details
Main Author: Strempel, Jannine M
Other Authors: Vercelli, Donata
Language:EN
Published: The University of Arizona. 2008
Subjects:
Online Access:http://hdl.handle.net/10150/194865