The Design, Synthesis, and Evaluation of Novel DFG-out Allosteric Kinase Inhibitors
Today, current drug discovery and lead generation efforts focus on high throughput screening of large chemical libraries as the primary source of lead candidates. A lack of investment in novel chemotype development by pharmaceutical companies over the last 15 years coupled with the concurrent merge...
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| Language: | EN |
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The University of Arizona.
2008
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| Online Access: | http://hdl.handle.net/10150/195661 |