Oocyte-Granulosa Cell Signaling in 4-Vinylcyclohexene Diepoxide-Induced Ovotoxicity

At birth, the mammalian ovary has a finite number of dormant primordial follicles. Repeated daily dosing of rats with the occupational chemical, 4- vinylcyclohexene diepoxide (VCD), depletes the ovary of small pre-antral follicles (primordial and primary follicles) through an increase in the natural...

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Bibliographic Details
Main Author: Fernandez, Shannon Marie
Other Authors: Hoyer, Patricia B.
Language:EN
Published: The University of Arizona. 2007
Subjects:
Online Access:http://hdl.handle.net/10150/195782