Oocyte-Granulosa Cell Signaling in 4-Vinylcyclohexene Diepoxide-Induced Ovotoxicity
At birth, the mammalian ovary has a finite number of dormant primordial follicles. Repeated daily dosing of rats with the occupational chemical, 4- vinylcyclohexene diepoxide (VCD), depletes the ovary of small pre-antral follicles (primordial and primary follicles) through an increase in the natural...
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Language: | EN |
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The University of Arizona.
2007
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Online Access: | http://hdl.handle.net/10150/195782 |