DNA Secondary Structures in the Promoters of Human VEGF and RET Genes and Their Roles in Gene Transcriptional Regulation

DNA Secondary Structures in the Promoters of Human VEGF and RET Genes and Their Roles in Gene Transcriptional Regulation

Unusual DNA secondary structures, especially G-quadruplexes and i-motifs, play important roles in gene transcriptional regulation and have been identified as novel drug targets. In this dissertation, I explored their formation in the human VEGF and RET promoters and their roles in gene transcription...

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Bibliographic Details
Main Author: Guo, Kexiao
Other Authors: Hurley, Laurence H.
Language:EN
Published: The University of Arizona. 2008
Subjects:
DNA secondary structures
Drug targeting
Promoter
RET
transcription factors
VEGF
Online Access:http://hdl.handle.net/10150/195943

Internet

http://hdl.handle.net/10150/195943

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