Expanding the Role of Gas-Phase Methods in Structural Biology: Characterization of Protein Quaternary Structure and Dynamics by Tandem Mass Spectrometry and Ion Mobility

This dissertation presents efforts to expand the role of mass spectrometry (MS) in structural biology. Determination of quaternary structure of a protein complex has been hindered by limited fragmentation from collision-induced dissociation (CID). As an alternative, surface-induced dissociation (S...

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Bibliographic Details
Main Author: Blackwell, Anne
Other Authors: Wysocki, Vicki H.
Language:en
Published: The University of Arizona. 2012
Subjects:
Online Access:http://hdl.handle.net/10150/238912