The TWEAK-Fn14 Ligand Receptor Axis Promotes Glioblastoma Cell Invasion and Survival Via Activation of Multiple GEF-Rho GTPase Signaling Systems

Glioblastoma (GB) is the highest grade and most common form of primary adult brain tumors, characterized by a highly invasive cell population. GB tumors develop treatment resistance and ultimately recur; the median survival is nearly fifteen months and importantly, the invading cell population is a...

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Bibliographic Details
Main Author: Fortin Ensign, Shannon Patricia
Other Authors: Tran, Nhan
Language:en
Published: The University of Arizona. 2013
Subjects:
GEF
Online Access:http://hdl.handle.net/10150/293463