HUGL and the Role of Polarity in Breast Cancer
Loss of polarity is a defining characteristic of epithelial cancers. The cytoskeletal proteins, HUGL1 and HUGL2, mediate polarity in epithelial cells through diversified roles in defining membrane identity and trafficking to the basolateral membrane. Importantly, an ortholog of these molecules can...
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| Language: | en |
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The University of Arizona.
2013
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| Online Access: | http://hdl.handle.net/10150/293491 |