Differential Splicing of the Large Sarcomeric Proteins Titin and Nebulin is Developmentally Regulated and is Altered in Genetically Engineered Mice

Skeletal muscle is composed of repeating units called sarcomeres which contain distinct sets of thin and thick filaments that slide past each other during contraction. In addition to these proteins a third filament called titin acts as a molecular spring and prevents overstretching of muscle. In s...

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Bibliographic Details
Main Author: Buck, Danielle Elizabeth
Other Authors: Granzier, Henk
Language:en_US
Published: The University of Arizona. 2014
Subjects:
Online Access:http://hdl.handle.net/10150/323451