Intrinsic Local Balancing of Hydrophobic and Hydrophilic Residues in Folded Protein Sequences
Protein sequences may evolve to avoid highly hydrophobic local regions of sequence, in part because such sequences promote nonnative aggregation. Hydrophobic local sequences are avoided in proteins even in buried regions, where native structure requirements tend to favor them. In this dissertation,...
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| Language: | en_US |
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The University of Arizona.
2015
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| Online Access: | http://hdl.handle.net/10150/596407 http://arizona.openrepository.com/arizona/handle/10150/596407 |