ITGB5 and AGFG1 variants are associated with severity of airway responsiveness

ITGB5 and AGFG1 variants are associated with severity of airway responsiveness

BACKGROUND:Airway hyperresponsiveness (AHR), a primary characteristic of asthma, involves increased airway smooth muscle contractility in response to certain exposures. We sought to determine whether common genetic variants were associated with AHR severity.METHODS:A genome-wide association study (G...

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Bibliographic Details
Main Authors: Himes, Blanca, Qiu, Weiliang, Klanderman, Barbara, Ziniti, John, Senter-Sylvia, Jody, Szefler, Stanley, Lemanske, Jr, Robert, Zeiger, Robert, Strunk, Robert, Martinez, Fernando, Boushey, Homer, Chinchilli, Vernon, Israel, Elliot, Mauger, David, Koppelman, Gerard, Nieuwenhuis, Maartje, Postma, Dirkje, Vonk, Judith, Rafaels, Nicholas, Hansel, Nadia, Barnes, Kathleen, Raby, Benjamin, Tantisira, Kelan, Weiss, Scott
Other Authors: Channing Division of Network Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA
Language:en
Published: BioMed Central 2013
Subjects:
Asthma
Airway hyperresponsiveness
Genome-wide association study
ITGB5
AGFG1
Online Access:Himes et al. BMC Medical Genetics 2013, 14:86 http://www.biomedcentral.com/1471-2350/14/86
http://hdl.handle.net/10150/610036
http://arizona.openrepository.com/arizona/handle/10150/610036

Internet

Himes et al. BMC Medical Genetics 2013, 14:86 http://www.biomedcentral.com/1471-2350/14/86
http://hdl.handle.net/10150/610036
http://arizona.openrepository.com/arizona/handle/10150/610036

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