Fast genome-wide pedigree quantitative trait loci analysis using MENDEL

The linkage era left a rich legacy of pedigree samples that can be used for modern genome-wide association sequencing (GWAS) or next-generation sequencing (NGS) studies. Family designs are naturally equipped to detect rare variants, control for population stratification, and facilitate the study of...

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Bibliographic Details
Main Authors: Zhou, Hua, Zhou, Jin, Sobel, Eric, Lange, Kenneth
Other Authors: Department of Statistics, North Carolina State University, Raleigh, NC27695 USA
Language:en
Published: BioMed Central 2014
Online Access:Zhou et al. BMC Proceedings 2014, 8(Suppl 1):S93 http://www.biomedcentral.com/1753-6561/8/S1/S93
http://hdl.handle.net/10150/610091
http://arizona.openrepository.com/arizona/handle/10150/610091