Chlorotyrosine protein adducts are reliable biomarkers of neutrophil-induced cytotoxicity in vivo

INTRODUCTION:A limitation for investigating the pathophysiological role of neutrophils in vivo is the lack of a reliable biomarker for neutrophil cytotoxicity in the liver. Therefore, we investigated if immunohistochemical detection of chlorotyrosine protein adducts can be used as a specific footpri...

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Bibliographic Details
Main Authors: Gujral, Jaspreet, Hinson, Jack, Jaeschke, Hartmut
Other Authors: Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
Language:en
Published: BioMed Central 2004
Online Access:Comparative Hepatology 2004, 3(Suppl 1):S48 http://www.comparative-hepatology.com/content/3/S1/S48
http://hdl.handle.net/10150/610122
http://arizona.openrepository.com/arizona/handle/10150/610122