Ontogeny of Unstable Chromosomes Formed by Telomere Replication Error

The integrity of the genome relies on the maintenance of chromosomes, the structural embodiment of the genetic material. Disruption of chromosome replication can lead to extensive genomic rearrangements, spanning kilobase (Kb) to megabase (Mb) regions. Some chromosome rearrangements are inherently d...

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Bibliographic Details
Main Author: Beyer, Tracey Elaine
Other Authors: Weinert, Ted
Language:en_US
Published: The University of Arizona. 2016
Subjects:
Online Access:http://hdl.handle.net/10150/621103
http://arizona.openrepository.com/arizona/handle/10150/621103