The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity.

The ER membrane-anchored ubiquitin ligase Hrd1 is a positive regulator of T-cell immunity.

Identification of positive regulators of T-cell immunity induced during autoimmune diseases is critical for developing novel therapies. The endoplasmic reticulum resident ubiquitin ligase Hrd1 has recently emerged as a critical regulator of dendritic cell antigen presentation, but its role in T-cell...

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Bibliographic Details
Main Authors: Xu, Yuanming, Zhao, Fang, Qiu, Quan, Chen, Kun, Wei, Juncheng, Kong, Qingfei, Gao, Beixue, Melo-Cardenas, Johanna, Zhang, Bin, Zhang, Jinping, Song, Jianxun, Zhang, Donna D, Zhang, Jianing, Fan, Yunping, Li, Huabin, Fang, Deyu
Other Authors: Univ Arizona, Coll Pharm, Dept Pharmacol & Toxicol
Language:en
Published: NATURE PUBLISHING GROUP 2016
Online Access:http://hdl.handle.net/10150/621464
http://arizona.openrepository.com/arizona/handle/10150/621464

Internet

http://hdl.handle.net/10150/621464
http://arizona.openrepository.com/arizona/handle/10150/621464

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