Monosialoganglioside-Containing Nanoliposomes Restore Endothelial Function Impaired by AL Amyloidosis Light Chain Proteins.

Monosialoganglioside-Containing Nanoliposomes Restore Endothelial Function Impaired by AL Amyloidosis Light Chain Proteins.

Light chain amyloidosis (AL) is associated with high mortality, especially in patients with advanced cardiovascular involvement. It is caused by toxicity of misfolded light chain proteins (LC) in vascular, cardiac, and other tissues. There is no treatment to reverse LC tissue toxicity. We tested the...

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Bibliographic Details
Main Authors: Franco, Daniel A, Truran, Seth, Weissig, Volkmar, Guzman-Villanueva, Diana, Karamanova, Nina, Senapati, Subhadip, Burciu, Camelia, Ramirez-Alvarado, Marina, Blancas-Mejia, Luis M, Lindsay, Stuart, Hari, Parameswaran, Migrino, Raymond Q
Other Authors: Univ Arizona, Coll Med
Language:en
Published: WILEY-BLACKWELL 2016
Subjects:
amyloid
endothelium
nanotechnology
oxidant stress
Online Access:http://hdl.handle.net/10150/621716
http://arizona.openrepository.com/arizona/handle/10150/621716

Internet

http://hdl.handle.net/10150/621716
http://arizona.openrepository.com/arizona/handle/10150/621716

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