A Novel Nuclear Function for the Interleukin-17 Signaling Adaptor Protein Act1

In the context of the human airway, interleukin-17A (IL-17A) signaling is associated with severe inflammation, as well as protection against pathogenic infection, particularly at mucosal surfaces such as the airway. The intracellular molecule Act1 has been demonstrated to be an essential mediator of...

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Bibliographic Details
Main Authors: Velichko, Sharlene, Zhou, Xu, Zhu, Lingxiang, Anderson, Johnathon David, Wu, Reen, Chen, Yin
Other Authors: Univ Arizona, Sch Pharm, Dept Pharmacol & Toxicol
Language:en
Published: PUBLIC LIBRARY SCIENCE 2016
Online Access:http://hdl.handle.net/10150/621947
http://arizona.openrepository.com/arizona/handle/10150/621947