Folate Functionalized PLGA Nanoparticles Loaded with Plasmid pVAX1-NH36: Mathematical Analysis of Release

Folate Functionalized PLGA Nanoparticles Loaded with Plasmid pVAX1-NH36: Mathematical Analysis of Release

Plasmid DNA (pVAX1-NH36) was encapsulated in nanoparticles of poly-dL-lactic-coglycolic ( PLGA) functionalized with polyethylene glycol ( PEG) and folic acid (PLGA-PEG-FA) without losing integrity. PLGA-PEG-FA nanoparticles loaded with pVAX1-NH36 (pDNA-NPs) were prepared by using a double emulsifica...

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Bibliographic Details
Main Authors: Gutiérrez-Valenzuela, Cindy, Guerrero-Germán, Patricia, Tejeda-Mansir, Armando, Esquivel, Reynaldo, Guzmán-Z, Roberto, Lucero-Acuña, Armando
Other Authors: Univ Arizona, Dept Chem & Environm Engn
Language:en
Published: MDPI AG 2016
Subjects:
drug delivery
pVAX1-NH36
mathematical analysis
copolymer synthesis
leishmaniasis
folate nanoparticles
Online Access:http://hdl.handle.net/10150/622432
http://arizona.openrepository.com/arizona/handle/10150/622432

Internet

http://hdl.handle.net/10150/622432
http://arizona.openrepository.com/arizona/handle/10150/622432

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