Reduced Nrf2 expression mediates the decline in neural stem cell function during a critical middle-age period

Reduced Nrf2 expression mediates the decline in neural stem cell function during a critical middle-age period

Although it is known that the regenerative function of neural stem/progenitor cells (NSPCs) declines with age, causal mechanisms underlying this phenomenon are not understood. Here, we systematically analyze subventricular zone (SVZ) NSPCs, in various groups of rats across the aging spectrum, using...

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Bibliographic Details
Main Authors: Corenblum, Mandi J., Ray, Sneha, Remley, Quentin W., Long, Min, Harder, Bryan, Zhang, Donna D., Barnes, Carol A., Madhavan, Lalitha
Other Authors: Univ Arizona, Dept Neurol
Language:en
Published: WILEY-BLACKWELL 2016
Subjects:
aging
oxidative stress
subventricular zone
redox
Nrf2
neural stem cells
Online Access:http://hdl.handle.net/10150/622598
http://arizona.openrepository.com/arizona/handle/10150/622598

Internet

http://hdl.handle.net/10150/622598
http://arizona.openrepository.com/arizona/handle/10150/622598

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