A basal cell defect promotes budding of prostatic intraepithelial neoplasia

A basal cell defect promotes budding of prostatic intraepithelial neoplasia

Basal cells in a simple secretory epithelium adhere to the extracellular matrix (ECM), providing contextual cues for ordered repopulation of the luminal cell layer. Early high-grade prostatic intraepithelial neoplasia (HG-PIN) tissue has enlarged nuclei and nucleoli, luminal layer expansion and geno...

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Bibliographic Details
Main Authors: Wang, Mengdie, Nagle, Raymond B., Knudsen, Beatrice S., Rogers, Gregory C., Cress, Anne E.
Other Authors: Univ Arizona, Ctr Canc, Coll Med, Dept Cellular & Mol Med
Language:en
Published: COMPANY OF BIOLOGISTS LTD 2017
Subjects:
Prostate
Neoplasia
Integrin
Laminin
Spheroids
Online Access:http://hdl.handle.net/10150/622647
http://arizona.openrepository.com/arizona/handle/10150/622647

Internet

http://hdl.handle.net/10150/622647
http://arizona.openrepository.com/arizona/handle/10150/622647

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