STAT1 Signaling in Astrocytes Is Essential for Control of Infection in the Central Nervous System

STAT1 Signaling in Astrocytes Is Essential for Control of Infection in the Central Nervous System

The local production of gamma interferon (IFN-gamma) is important to control Toxoplasma gondii in the brain, but the basis for these protective effects is not fully understood. The studies presented here reveal that the ability of IFN-gamma to inhibit parasite replication in astrocytes in vitro is d...

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Main Authors: Hidano, Shinya, Randall, Louise M., Dawson, Lucas, Dietrich, Hans K., Konradt, Christoph, Klover, Peter J., John, Beena, Harris, Tajie H., Fang, Qun, Turek, Bradley, Kobayashi, Takashi, Hennighausen, Lothar, Beiting, Daniel P., Koshy, Anita A., Hunter, Christopher A.
Other Authors: Univ Arizona, Dept Neurol, Dept Immunobiol, Inst BIO5
Language:en
Published: AMER SOC MICROBIOLOGY 2016
Online Access:http://hdl.handle.net/10150/622765
http://arizona.openrepository.com/arizona/handle/10150/622765

Internet

http://hdl.handle.net/10150/622765
http://arizona.openrepository.com/arizona/handle/10150/622765

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