DNA Replication Defects in the Telomere Induce Chromosome Instability in a Single Cell Cycle
Errors in DNA replication can cause chromosome instability and gross chromosomal rearrangements (GCRs). For my thesis work I investigate how chromosome instability can originate in the telomere. Here I report how defects in Cdc13, a telomere specific protein, lead to chromosome instability and GCRs...
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| Language: | en_US |
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The University of Arizona.
2016
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| Online Access: | http://hdl.handle.net/10150/622910 http://arizona.openrepository.com/arizona/handle/10150/622910 |