Identification of G-quadruplexes in long functional RNAs using 7-deazaguanine RNA

RNA G-quadruplex (G4) structures are thought to affect biological processes, including translation and pre-mRNA splicing, but it is not possible at present to demonstrate that they form naturally at specific sequences in long functional RNA molecules. We developed a new strategy, footprinting of lon...

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Bibliographic Details
Main Authors: Weldon, Carika, Behm-Ansmant, Isabelle, Hurley, Laurence H, Burley, Glenn A, Branlant, Christiane, Eperon, Ian C, Dominguez, Cyril
Other Authors: College of Pharmacy and BIO5 Institute, University of Arizona
Language:en
Published: NATURE PUBLISHING GROUP 2016
Online Access:http://hdl.handle.net/10150/623077
http://arizona.openrepository.com/arizona/handle/10150/623077