Islet adaptations in fetal sheep persist following chronic exposure to high norepinephrine.

Islet adaptations in fetal sheep persist following chronic exposure to high norepinephrine.

Complications in pregnancy elevate fetal norepinephrine (NE) concentrations. Previous studies in NE-infused sheep fetuses revealed that sustained exposure to high NE resulted in lower expression of α2-adrenergic receptors in islets and increased insulin secretion responsiveness after acutely termina...

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Bibliographic Details
Main Authors: Chen, Xiaochuan, Kelly, Amy C, Yates, Dustin T, Macko, Antoni R, Lynch, Ronald M, Limesand, Sean W
Other Authors: Univ Arizona, Sch Anim & Comparat Biomed Sci
Language:en
Published: BIOSCIENTIFICA LTD 2017
Subjects:
beta-cell
adrenergic receptor
islets of Langerhans
catecholamine
fetal stress
Online Access:http://hdl.handle.net/10150/623222
http://arizona.openrepository.com/arizona/handle/10150/623222

Internet

http://hdl.handle.net/10150/623222
http://arizona.openrepository.com/arizona/handle/10150/623222

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