Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease

Metabolites derived from dietary choline and L-carnitine, such as trimethylamine N-oxide and betaine, have recently been identified as novel risk factors for atherosclerosis in mice and humans. We sought to identify genetic factors associated with plasma betaine levels and determine their effect on...

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Bibliographic Details
Main Authors: Hartiala, Jaana A., Wilson Tang, W. H., Wang, Zeneng, Crow, Amanda L., Stewart, Alexandre F. R., Roberts, Robert, McPherson, Ruth, Erdmann, Jeanette, Willenborg, Christina, Hazen, Stanley L., Allayee, Hooman
Language:en
Published: NATURE PUBLISHING GROUP 2016
Online Access:http://hdl.handle.net/10150/623257
http://arizona.openrepository.com/arizona/handle/10150/623257