Zinc complexes of diflunisal: Synthesis, characterization, structure, antioxidant activity, and in vitro and in silico study of the interaction with DNA and albumins

Zinc complexes of diflunisal: Synthesis, characterization, structure, antioxidant activity, and in vitro and in silico study of the interaction with DNA and albumins

From the reaction of ZnCl2 with the non-steroidal anti-inflammatory drug diflunisal (Hdifl), complex [Zn(difl-O)(2)(MeOH)(4)], 1 was formed, while in the presence of a N,N'-donor heterocyclic ligand 2,2'-bipyridylamine (bipyam), 2,2'-bipyridine (bipy), 1,10-phenanthroline (phen) and 2...

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Main Authors: Tarushi, Alketa, Kakoulidou, Chrisoula, Raptopoulou, Catherine P., Psycharis, Vassilis, Kessissoglou, Dimitris P., Zoi, Ioanna, Papadopoulos, Athanasios N., Psomas, George
Other Authors: Department of Chemistry and Biochemistry, University of Arizona
Language:en
Published: ELSEVIER SCIENCE INC 2017
Subjects:
Diflunisal
Zinc complexes
Biological activity
Interaction with DNA
Molecular docking
Online Access:http://hdl.handle.net/10150/623572
http://arizona.openrepository.com/arizona/handle/10150/623572

Internet

http://hdl.handle.net/10150/623572
http://arizona.openrepository.com/arizona/handle/10150/623572

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