Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset

Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset

New approaches are needed for the treatment of patients with T-cell acute lymphoblastic leukemia (T-ALL) who fail to achieve remission with chemotherapy. Analysis of the effects of pan-PIM protein kinase inhibitors on human T-ALL cell lines demonstrated that the sensitive cell lines expressed higher...

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Bibliographic Details
Main Authors: Padi, Sathish K.R., Luevano, Libia A., An, Ningfei, Pandey, Ritu, Singh, Neha, Song, Jin H., Aster, Jon C., Yu, Xue-Zhong, Mehrotra, Shikhar, Kraft, Andrew S.
Other Authors: Univ Arizona, Ctr Canc
Language:en
Published: IMPACT JOURNALS LLC 2017
Subjects:
PIM kinase
T-ALL
ETP-ALL
tyrosine kinase inhibitor
ponatinib
Online Access:http://hdl.handle.net/10150/624055
http://arizona.openrepository.com/arizona/handle/10150/624055

Internet

http://hdl.handle.net/10150/624055
http://arizona.openrepository.com/arizona/handle/10150/624055

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