Targeting the Transcription of RET Oncogene in Medullary Thyroid Carcinoma Using Drug-Like Small Molecules
Dominant-activating mutations in the RET (Rearranged during transfection) proto-oncogene, which encodes a receptor tyrosine kinase, was identified as the major cause for the development of medullary thyroid carcinoma (MTC). Hence, the RET protein has been explored as an excellent molecular target fo...
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| Language: | en_US |
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The University of Arizona.
2017
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| Online Access: | http://hdl.handle.net/10150/624541 http://arizona.openrepository.com/arizona/handle/10150/624541 |