Investigating the Effects of Tropomyosin D230N and cTnT R92L on the Tropomyosin Overlap Region

The progression of genetically inherited cardiomyopathies from an altered protein structure to the clinical presentation of the disease is not well understood. One of the main roadblocks to mechanistic insight remains a lack of high-resolution structural information of multiprotein complexes within...

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Bibliographic Details
Main Author: McConnell, Mark
Other Authors: Tardiff, Jil C.
Language:en_US
Published: The University of Arizona. 2017
Subjects:
Online Access:http://hdl.handle.net/10150/624576
http://arizona.openrepository.com/arizona/handle/10150/624576