Regulation of Cx37 channel and growth-suppressive properties by phosphorylation

Growth suppression mediated by connexin 37 (Cx37; also known as GJA4) requires interaction between its C-terminus and functional pore-forming domain. Using rat insulinoma cells, we show that Cx37 induces cell death and cell cycle arrest, and slowed cell cycling. Whether differential phosphorylation...

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Bibliographic Details
Main Authors: Jacobsen, Nicole L., Pontifex, Tasha K., Li, Hanjun, Solan, Joell L., Lampe, Paul D., Sorgen, Paul L., Burt, Janis M.
Other Authors: Univ Arizona, Dept Physiol
Language:en
Published: COMPANY OF BIOLOGISTS LTD 2017
Subjects:
Online Access:http://hdl.handle.net/10150/625983
http://arizona.openrepository.com/arizona/handle/10150/625983