Pak2 regulates myeloid-derived suppressor cell development in mice
Myeloid-derived suppressor cells (MDSCs) are CD11b(+)Gr1(+) cells that induce T-cell hyporesponsiveness, thus impairing antitumor immunity. We have previously reported that disruption of Pak2, a member of the p21-activated kinases (Paks), in hematopoietic stem/progenitor cells (HSPCs) induces myeloi...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Language: | en |
| Published: |
AMER SOC HEMATOLOGY
2017
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| Online Access: | http://hdl.handle.net/10150/626038 http://arizona.openrepository.com/arizona/handle/10150/626038 |