Perimenopause and emergence of an Alzheimer’s bioenergetic phenotype in brain and periphery

After advanced age, female sex is the major risk factor for Alzheimer's disease (AD). The biological mechanisms underlying the increased AD risk in women remain largely undetermined. Preclinical studies identified the perimenopause to menopause transition, a neuroendocrine transition state uniq...

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Bibliographic Details
Main Authors: Mosconi, Lisa, Berti, Valentina, Guyara-Quinn, Crystal, McHugh, Pauline, Petrongolo, Gabriella, Osorio, Ricardo S., Connaughty, Christopher, Pupi, Alberto, Vallabhajosula, Shankar, Isaacson, Richard S., de Leon, Mony J., Swerdlow, Russell H., Brinton, Roberta Diaz
Other Authors: Univ Arizona, Coll Med, Dept Pharmacol
Language:en
Published: PUBLIC LIBRARY SCIENCE 2017
Online Access:http://hdl.handle.net/10150/626072
http://arizona.openrepository.com/arizona/handle/10150/626072