Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment

Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment

The current study employed next-generation RNA sequencing to examine gene expression differences related to brain aging, cognitive decline, and hippocampal subfields. Young and aged rats were trained on a spatial episodic memory task. Hippocampal regions CA1, CA3, and the dentate gyrus were isolated...

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Bibliographic Details
Main Authors: Ianov, Lara, De Both, Matt, Chawla, Monica K., Rani, Asha, Kennedy, Andrew J., Piras, Ignazio, Day, Jeremy J., Siniard, Ashley, Kumar, Ashok, Sweatt, J. David, Barnes, Carol A., Huentelman, Matthew J., Foster, Thomas C.
Other Authors: Univ Arizona, Evelyn F McKnight Brain Inst
Language:en
Published: FRONTIERS MEDIA SA 2017
Subjects:
aging
hippocampus
cognitive function
transcription
gene expression
Illumina HiSeq
Ion proton
Online Access:http://hdl.handle.net/10150/626430
http://arizona.openrepository.com/arizona/handle/10150/626430

Internet

http://hdl.handle.net/10150/626430
http://arizona.openrepository.com/arizona/handle/10150/626430

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