Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification

Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification

Establishment of a functional vascular network is rate-limiting in embryonic development, tissue repair and engineering. During blood vessel formation, newly generated endothelial cells rapidly expand into primitive plexi that undergo vascular remodeling into circulatory networks, requiring coordina...

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Bibliographic Details
Main Authors: Fang, Jennifer S., Coon, Brian G., Gillis, Noelle, Chen, Zehua, Qiu, Jingyao, Chittenden, Thomas W., Burt, Janis M., Schwartz, Martin A., Hirschi, Karen K.
Other Authors: Univ Arizona, Dept Physiol, Coll Med
Language:en
Published: NATURE PUBLISHING GROUP 2017
Online Access:http://hdl.handle.net/10150/626459
http://arizona.openrepository.com/arizona/handle/10150/626459

Internet

http://hdl.handle.net/10150/626459
http://arizona.openrepository.com/arizona/handle/10150/626459

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