Activation of ventral tegmental area dopaminergic neurons reverses pathological allodynia resulting from nerve injury or bone cancer

Activation of ventral tegmental area dopaminergic neurons reverses pathological allodynia resulting from nerve injury or bone cancer

Chronic pain induced by nerve damage due to trauma or invasion of cancer to the bone elicits severe ongoing pain as well as hyperalgesia and allodynia likely reflecting adaptive changes within central circuits that amplify nociceptive signals. The present study explored the possible contribution of...

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Bibliographic Details
Main Authors: Watanabe, Moe, Narita, Michiko, Hamada, Yusuke, Yamashita, Akira, Tamura, Hideki, Ikegami, Daigo, Kondo, Takashige, Shinzato, Tatsuto, Shimizu, Takatsune, Fukuchi, Yumi, Muto, Akihiro, Okano, Hideyuki, Yamanaka, Akihiro, Tawfik, Vivianne L, Kuzumaki, Naoko, Navratilova, Edita, Porreca, Frank, Narita, Minoru
Other Authors: Univ Arizona, Arizona Hlth Sci Ctr, Dept Pharmacol
Language:en
Published: SAGE PUBLICATIONS INC 2018
Subjects:
Neuropathic pain
cancer pain
dopamine
mesolimbic dopaminergic neurons
optogenetics
Online Access:http://hdl.handle.net/10150/627057
http://arizona.openrepository.com/arizona/handle/10150/627057

Internet

http://hdl.handle.net/10150/627057
http://arizona.openrepository.com/arizona/handle/10150/627057

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