Changes in Sensitivity to the Effects of Atrazine on the Luteinizing Hormone Surge in Female Sprague-Dawley Rats after Repeated Daily Doses: Correlation with Liver Enzyme Expression
BackgroundAtrazine suppression of the LH surge slowly develops over time and peaks after 4 days; sensitivity to atrazine decreases after 8 or 14 days of dosing. Adaptation of the LH response was correlated with increased phase I and phase II liver enzyme activity/expression. MethodsThe effect of atr...
Main Authors: | Breckenridge, Charles B., Foradori, Chad D., Sawhney Coder, Pragati, Simpkins, James W., Sielken, Robert L., Handa, Robert J. |
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Other Authors: | Univ Arizona, Dept Basic Med Sci, Coll Med |
Language: | en |
Published: |
WILEY
2018
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Subjects: | |
Online Access: | http://hdl.handle.net/10150/627193 http://arizona.openrepository.com/arizona/handle/10150/627193 |
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