Breaking the Senescence: Inhibition of ATM Allows S9 Cells to Re-Enter Cell Cycle
abstract: The Philadelphia chromosome in humans, is on oncogenic translocation between chromosomes 9 and 22 that gives rise to the fusion protein BCR-Abl. This protein is constitutively active resulting in rapid and uncontrolled cell growth in affected cells. The BCR-Abl protein is the hallmark feat...
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| Format: | Dissertation |
| Language: | English |
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2011
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| Online Access: | http://hdl.handle.net/2286/R.I.14447 |