Influence of Histone Deacetylase Inhibitors on Polymer Mediated Transgene Delivery

Influence of Histone Deacetylase Inhibitors on Polymer Mediated Transgene Delivery

abstract: The effects of specific histone deacetylase inhibitors (HDACi) on transgene expression in combination with a novel polymer as a delivery vehicle are investigated in this research. Polymer vectors, although safer than viruses, are notorious for low levels of gene expression. In this investi...

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Bibliographic Details
Other Authors: Lehrman, Jennifer Nicole (Author)
Format: Dissertation
Language:English
Published: 2012
Subjects:
Biomedical engineering
Chemical engineering
combinational therapy
gene therapy
histone deacetylase inhibitors
polymer vector
prostate cancer
transgene expression
Online Access:http://hdl.handle.net/2286/R.I.14915

Internet

http://hdl.handle.net/2286/R.I.14915

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