Synthesis Of Halo Alkyl And Alkenyl Ortho-Carboxy Aryls And Bromo Nitro Lactones As Inhibitors Of Protein Tyrosine Phosphatases And Cancer Cell Growth
abstract: Changes to a cell's DNA can result in cancer, which is permanently sustained cellular proliferation. When malfunctioning genes, oncogenes, were verified to be of human origin in the 1970s, drugs were designed to target their encoded, abnormal enzymes. Tyrosine kinases have been establ...
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| Format: | Doctoral Thesis |
| Language: | English |
| Published: |
2012
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| Online Access: | http://hdl.handle.net/2286/R.I.16008 |