Structure-Function Study of Telomerase RNA from Evolutionary Disparate Species: Remarkable Divergence in Gross Architecture with the Preservation of Critical Universal Structural Elements
abstract: Telomerase enzyme is a truly remarkable enzyme specialized for the addition of short, highly repetitive DNA sequences onto linear eukaryotic chromosome ends. The telomerase enzyme functions as a ribonucleoprotein, minimally composed of the highly conserved catalytic telomerase reverse tra...
Other Authors: | |
---|---|
Format: | Doctoral Thesis |
Language: | English |
Published: |
2015
|
Subjects: | |
Online Access: | http://hdl.handle.net/2286/R.I.29772 |