Structure-Function Study of Telomerase RNA from Evolutionary Disparate Species: Remarkable Divergence in Gross Architecture with the Preservation of Critical Universal Structural Elements

abstract: Telomerase enzyme is a truly remarkable enzyme specialized for the addition of short, highly repetitive DNA sequences onto linear eukaryotic chromosome ends. The telomerase enzyme functions as a ribonucleoprotein, minimally composed of the highly conserved catalytic telomerase reverse tra...

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Bibliographic Details
Other Authors: Podlevsky, Joshua David (Author)
Format: Doctoral Thesis
Language:English
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/2286/R.I.29772