Generation of isogenic pluripotent stem cell lines for study of APOE, an Alzheimer’s risk factor
abstract: Alzheimer’s disease (AD), despite over a century of research, does not have a clearly defined pathogenesis for the sporadic form that makes up the majority of disease incidence. A variety of correlative risk factors have been identified, including the three isoforms of apolipoprotein E (Ap...
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Format: | Dissertation |
Language: | English |
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2017
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Online Access: | http://hdl.handle.net/2286/R.I.43973 |