Targeted Knockdown of MYC in AML Cells Using G-quadruplex Interacting Small Molecules

abstract: Acute Myeloid Leukemia (AML) is a disease that occurs when genomic changes alter expression of key genes in myeloid blood cells. These changes cause them to resume an undifferentiated state, proliferate, and maintain growth throughout the body. AML is commonly treated with chemotherapy, bu...

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Bibliographic Details
Other Authors: Turnidge, Megan (Author)
Format: Dissertation
Language:English
Published: 2017
Subjects:
MYC
Online Access:http://hdl.handle.net/2286/R.I.45025